Exploring the efficacy of different agents for treatment of dentin hypersensitivity

The objective of this study was to determine the efficacy of casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACP), bonding agent, and herbal agent for the reduction of dentin hypersensitivity (DH).

A multi-centered, single-blinded study was carried out, comprising 210 systemically healthy subjects with at least 2 sensitive teeth. Three sessions of therapy were administered to each of the three groups, with a 72-h interval in between administrations. The hypersensitive teeth were subjected to tactile and evaporative stimuli at baseline, after the 1^st, 2^nd, and 3^rd sessions, and then after the 1^st week and 4^th week posttreatment. On the Visual Analog Scale, the individuals' reactions to the stimuli were noted. Furthermore, the Dentin Hypersensitivity Experience Questionnaire was given to the subjects and was asked to fill on the basis of 5-point Likert scale at baseline and after 1 month of the treatment.

The collected data showed that all the three agents are effective in the treatment of DH; however, CPP-ACP is the most effective followed by bonding agent followed by herbal agents. Treatment of DH showed a positive impact on the quality of life of all subjects.

This study showed that, following a 1-month follow-up, the CPP-ACP, bonding agent, and herbal agent were successful in lowering DH and improving the participants' quality of life.