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Updated: Apr 7, 2026

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
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Decoding Sarcoma Drug Resistance: From Molecular Mechanisms to Precision Interventions.

Guizhen Lyu1, Dongbing Li2

  • 1Dongguan Key Laboratory of Clinical Medical Test Diagnostic Technology for Oncology, Dongguan Labway Clinical Laboratory Co., Ltd., Dongguan, 523429, Guangdong, China.

Anti-Cancer Agents in Medicinal Chemistry
|April 6, 2026
PubMed
Summary

Sarcoma drug resistance is complex, involving molecular and microenvironmental factors. Precision medicine strategies, combining mechanistic insights with biomarker-guided therapies, offer a promising approach to improve patient outcomes.

Keywords:
Sarcoma heterogeneitybiomarker- guided treatment.combination strategiesdrug resistance mechanismsprecision therapytumor microenvironment

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