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Published on: January 6, 2014
Follicular Dendritic Cell Sarcoma in an Adolescent Patient
Hannah Glanz1, Allison Weisnicht1, Kristin Bradley2
1Department of Pediatrics, Division of Pediatric Hematology, Oncology, Transplant and Cellular Therapy, University of Wisconsin School of Medicine and Public Health, UW Carbone Cancer Center, Madison, WI.
Background:
Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm that usually occurs in the adult population. Since its first description, only 9 cases have been reported in children. Due to its rarity, there is no standardized treatment.
Observations:
We present a case of multiply-relapsed FDCS in an adolescent patient that responded favorably to chemotherapy.
Conclusion:
For many, wide local excision of FDCS may be curative. However, more research is required to determine the best course of treatment for patients requiring adjuvant chemotherapy or radiation. In addition, expanding genetic research has the potential to provide targeted therapy in the future.
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