Related Experiment Video
Updated: Apr 7, 2026

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp
Published on: February 3, 2014
Physics-informed neural network for predicting in vacuo vocal fold eigenmodes: A proof of concept study
Mohd Ethar M Al Khasawneh1, Michael Döllinger1, Zhaoyan Zhang2
1Division of Phoniatrics and Pediatric Audiology, Department of Otorhinolaryngology Head & Neck Surgery, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg, Waldstrasse 1, 91054 Erlangen, Germany.
A physics-informed neural network accurately computes vocal fold eigenmodes in real-time. This machine learning approach shows strong agreement with traditional methods for lower-order modes, offering an efficient computational tool.
Area of Science:
- Computational physics
- Machine learning in biomechanics
- Vocal fold dynamics
Background:
- Accurate computation of vocal fold eigenmodes is crucial for understanding voice production.
- Traditional methods like finite-element analysis can be computationally intensive.
- Real-time prediction methods are needed for dynamic simulations and clinical applications.
Purpose of the Study:
- To develop and evaluate a machine learning approach for real-time computation of in vacuo vocal fold eigenmodes.
- To integrate governing equations of vocal fold dynamics into a physics-informed neural network.
- To assess the accuracy and efficiency of the proposed method compared to finite-element results.
Main Methods:
- Training a physics-informed neural network (PINN) to predict vocal fold eigenmodes and eigenfrequencies.
- Integrating the governing equations of vocal fold dynamics into the neural network architecture.
- Comparing PINN predictions with results from finite-element method (FEM) simulations.
Main Results:
- The PINN accurately predicted physically consistent modal shapes and eigenfrequency estimates.
- Strong agreement was observed between PINN results and FEM for lower-order modes.
- Mean relative errors below 6% in eigenfrequency prediction and cosine correlation values near 1 for eigenmodes were achieved.
- Prediction accuracy decreased for higher-order modes.
Conclusions:
- Physics-informed neural networks offer an accurate and efficient method for real-time computation of vocal fold eigenmodes.
- This approach holds potential for advancing voice production research and clinical diagnostics.
- Further refinement may improve accuracy for higher-order modes.
Related Concept Videos
Perceiving Loudness, Pitch, and Location
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by...
Perception of Sound Waves
The pitch of a sound depends on the frequency and the pressure amplitude of the source. Two sounds of the same...
Standing Waves in a Cavity
Neural Control of Respiration
Respiratory Centers in the Brainstem
Two primary areas comprise the respiratory center: the medullary respiratory center in the medulla oblongata and the pontine respiratory group in the pons. The...
Linear Approximation in Frequency Domain
In contrast, nonlinear systems do not inherently possess these properties. However, for small deviations around an operating point, a nonlinear system can often be approximated as linear....
Neural Regulation

