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Related Experiment Video

Updated: Apr 7, 2026

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
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Cyanoacrylate Adhesive for Retinal Tear Repair: A Contemporary Approach in Rhegmatogenous Retinal Detachment Surgery.

Stanislao Rizzo1,2,3, Patrizio Bernardinelli1,4, Nicola Claudio D'Onofrio1,2

  • 1Ophthalmology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Retinal Cases & Brief Reports
|April 6, 2026
PubMed
Summary

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Therapeutic advances in ophthalmology·2026
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1 MONTH VS. 3 MONTHS HEAVY SILICONE OIL TAMPONADE IN COMPLEX RHEGMATOGENOUS RETINAL REDETACHMENT.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde·2026
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Horizontal Scleral Incisions for Fixation of Carlevale Intraocular Lens: A Useful Surgical Variant.

Retinal cases & brief reports·2026

Cyanoacrylate adhesive shows promise for repairing retinal tears in rhegmatogenous retinal detachment (RRD). This innovative technique avoids the need for postoperative prone positioning, offering a valuable alternative for specific patient cases.

Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Biomaterials

Background:

  • Rhegmatogenous retinal detachment (RRD) poses a significant risk to vision.
  • Traditional RRD repair often requires prolonged postoperative prone positioning.
  • Previous vitrectomy and retinopexy procedures complicated this patient's RRD management.

Purpose of the Study:

  • To evaluate cyanoacrylate adhesive for retinal tear repair in RRD.
  • To assess anatomical and functional outcomes of this novel technique.
  • To explore advantages over conventional RRD repair methods.

Main Methods:

  • A case study involving a patient with complex RRD and prior failed vitrectomy.
  • Surgical repair utilized 23-gauge pars plana vitrectomy and cyanoacrylate adhesive to seal retinal tears.
Keywords:
CyanoacrylateRetinal AdhesiveRetinal DetachmentRetinal SurgeryRetinal Tear RepairRhegmatogenous Retinal DetachmentScleral AdhesiveTissue AdhesiveVitrectomyVitreoretinal Surgery

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  • Perfluorocarbon liquid (PFCL) was used for retinal stabilization; no intraocular tamponade was employed.
  • Main Results:

    • Successful retinal reattachment achieved and maintained for six months.
    • Significant visual acuity improvement from hand motion to counting fingers by two months.
    • No complications such as proliferative vitreoretinopathy or adhesive migration were observed.

    Conclusions:

    • Cyanoacrylate adhesive is a promising option for complex RRD repair.
    • This method eliminates the need for postoperative head positioning.
    • It offers a valuable alternative, particularly for patients unable to adhere to positioning protocols.