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Penicillin Allergy and Management in the Dental Setting: A Scoping Review
Ifeanyichukwu Ezeliorah1, Aviv Ouanounou2
1Resident, Dental Anesthesia Specialty Program, Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.
None:
Penicillins are important beta-lactam antibiotics that are frequently used in dentistry. Many odontogenic infections are sensitive to penicillin. An allergic reaction to penicillin is an undesirable and life-threatening response mounted by the immune system. Penicillin allergies can be either Type I Anaphylactic reactions or Type IV Delayed reactions. Concerns regarding penicillin allergy over-reporting and the prescribing of potentially less effective yet more expensive alternatives have been topics of discussion in recent years. This article aims to provide a comprehensive review of the literature on penicillin allergy epidemiology, risk stratification, clinical manifestations, tests needed for allergy confirmation, allergic reaction management, antibiotic stewardship, and alternative medications to use in penicillin-allergic patients.
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