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Regulation of long non-coding RNAs by essential oils: Therapeutic implications in human diseases
Lívia da Cunha Agostini1, Mariane Ster da Silva Teixeira1, Glenda Nicioli da Silva1,2
1Universidade Federal de Ouro Preto, Escola de Farmácia, Programa de Pós-Graduação em Ciências Farmacêuticas (CiPharma), Ouro Preto, MG, Brazil.
None:
Essential oils are natural substances with broad therapeutic potential due to their antioxidant, anti-inflammatory, and anticancer properties. Recent studies have demonstrated that these compounds can modulate the expression of non-coding RNAs, such as lncRNAs, miRNAs, and circRNAs, which play crucial roles in post-transcriptional and epigenetic regulation in various pathological conditions. This modulation influences key biological processes, including apoptosis, drug resistance, inflammation, cell differentiation, and cognitive function. Therefore, the regulation of ncRNAs by essential oils emerges as a promising strategy for the development of novel therapeutic approaches in cancer, respiratory, joint, and neurodegenerative diseases. This review summarizes the latest findings on the ability of essential oils to modulate ncRNAs, highlighting their potential in the prevention and treatment of a wide range of human diseases.
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lncRNA - Long Non-coding RNAs
lncRNA - Long Non-coding RNAs
Types of RNA
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
Types of RNA
RNA Performs Diverse...
Regulation of Expression at Multiple Steps
Translational Regulation

