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Updated: Apr 8, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Demystifying menopausal hormone therapy prescribing
Karen Magraith1, Christina Jang2
1BMBS, FRACGP, General Practitioner, General Practice Plus, South Hobart, Tas; Clinical Senior Lecturer, University of Tasmania, Hobart, Tas; President, Australasian Menopause Society, Healesville, Vic.
Background:
Menopause and perimenopause are associated with vasomotor symptoms and other symptoms that can affect quality of life. Menopausal hormone therapy (MHT) improves menopausal symptoms and reduces the risk of osteoporosis and fracture.
Objective:
This article provides an updated overview of the basic principles of prescribing MHT, including the risks and benefits and practical information for tailoring treatment to the individual.
Discussion:
Women presenting at menopause should have a comprehensive assessment including updated health screening and promotion of a healthy lifestyle. MHT can be offered to women with symptoms in the absence of contraindications, following a discussion about risks and benefits. MHT comprises systemic oestrogen, and for those with an intact uterus, a progestogen.
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