Primitive Neuroectodermal Kidney Tumor in Adults. A Systematic Review
Eloísa Cabello-Gómez1, Inés Rivero-Belenchón1, Carmen Belén Congregado-Ruiz1
1Urology Department, Virgen del Rocío University Hospital, 41013 Sevilla, Spain.
Archivos Espanoles De Urologia
|April 7, 2026
Summary
Renal primitive neuroectodermal tumors (rPNET) are aggressive cancers in adults, often diagnosed late. Early multimodal treatment including surgery and chemotherapy is crucial for improving outcomes in these rare kidney tumors.
Area of Science:
- Oncology
- Urologic Oncology
- Pathology
Background:
- Renal primitive neuroectodermal tumor (rPNET) is a rare malignancy predominantly affecting young adults.
- Diagnosis typically relies on histopathology, and the condition carries a poor prognosis, necessitating a multidisciplinary treatment approach.
Conclusions:
- Adult rPNET is a rare, aggressive tumor often diagnosed at advanced stages.
- A multimodal strategy involving surgery, systemic chemotherapy, and potentially radiotherapy, planned by a multidisciplinary team in specialized centers, is recommended.
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