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Diagnostic Accuracy of Ultrasonography for Knee Pathologies: A Prospective Comparative Study With MRI
Priyanka Priyanka1, Rupali Sharma1, Roopali Mangotra1
1Radiodiagnosis, Government Medical College and Hospital, Jammu, IND.
Cureus
|April 7, 2026
Summary
High-resolution ultrasonography (HRUS) shows high specificity for superficial knee structures but limited visualization of cruciate ligaments. It can be a valuable screening tool, especially in resource-limited settings, complementing MRI.
Area of Science:
- Orthopedics
- Radiology
- Medical Imaging
Background:
- Knee joint pathologies frequently require imaging for diagnosis.
- Magnetic resonance imaging (MRI) is the gold standard for knee imaging due to superior soft tissue resolution but is costly and time-consuming.
- High-resolution ultrasonography (HRUS) offers high soft tissue resolution for superficial structures, is cost-effective, and readily available.
Purpose of the Study:
- To compare the diagnostic performance of HRUS with MRI for knee joint pathologies.
- To evaluate the sensitivity, specificity, and accuracy of HRUS in detecting various knee structures.
Main Methods:
- A prospective study involving 50 patients with symptomatic knee joints.
- All patients underwent HRUS followed by MRI (1.5 T Siemens) with a standard knee protocol.
- MRI served as the reference standard, with findings compared to HRUS to calculate diagnostic indices.
Main Results:
- Anterior cruciate ligament and medial meniscus were most commonly affected.
- HRUS demonstrated low sensitivity but high specificity for meniscal injuries.
- Excellent diagnostic performance (near 100% specificity) was observed for superficial structures like collateral ligaments, tendons, synovitis, collections, and popliteal cysts.
- Joint effusion detection had 94.7% sensitivity and 100% specificity.
- Cruciate ligaments were poorly visualized by HRUS.
Conclusions:
- While MRI remains the gold standard for comprehensive knee evaluation, HRUS exhibits strong specificity and good diagnostic utility for superficial soft tissue abnormalities.
- HRUS can serve as an effective screening tool, particularly in resource-limited environments, to identify superficial knee pathologies.
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