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Related Concept Videos

Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

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Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
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Errors occurring during blood pressure monitoring01:25

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Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
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Blood Pressure01:30

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Blood pressure (BP) is the pressure or force of blood exerted on the artery's walls as it circulates through the body. It is essential for maintaining blood flow throughout the body.
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the...
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Blood Pressure01:24

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The movement of blood in a human body, commonly referred to as blood flow, is determined by the volume of blood that traverses a certain section of the bodily system per unit time. It is the rhythmic contraction of the heart's ventricles that primarily instigates this movement. As the ventricles contract, blood is forced into the prominent arteries, which then flow from areas of greater pressure to lower pressure areas. This movement continues into smaller arteries and arterioles and...
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Factors affecting Blood pressure01:28

Factors affecting Blood pressure

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Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
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Measurement of Blood Pressure01:17

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Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
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Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
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Blood Pressure Control and Mortality Among US Veterans.

Masaaki Yamada1,2, Benjamin R Griffin1,2, Qianyi Shi1,2

  • 1Center for Access & Delivery Research and Evaluation, Iowa City VAMC, IA (M.Y., B.R.G., Q.S., M.L.S., M.K.G., H.S.R., B.C.L., M.S.V.S., D.I.J.).

Hypertension (Dallas, Tex. : 1979)
|April 7, 2026
PubMed
Summary
This summary is machine-generated.

Lower mortality risk in US Veterans was linked to systolic blood pressure (BP) between 130-139 mmHg. This suggests higher BP targets may be suitable for older adults with comorbidities.

Keywords:
agedblood pressurehypertensionveterans

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Area of Science:

  • Cardiology
  • Public Health
  • Geriatrics

Background:

  • Clinical trials show intensive blood pressure (BP) control reduces mortality and cardiovascular disease.
  • Real-world BP measurements frequently deviate from standardized protocols.
  • The impact of real-world systolic BP on mortality in US Veterans requires evaluation.

Purpose of the Study:

  • To assess the association between real-world systolic BP levels and all-cause mortality in a large cohort of US Veterans.
  • To determine if current BP control guidelines are optimal for the diverse Veteran population.
  • To inform clinical practice regarding appropriate BP targets, particularly for older adults with comorbidities.

Main Methods:

  • A retrospective cohort study of over 2.3 million US Veterans with hypertension was conducted.
  • Systolic BP was analyzed as a time-dependent covariate across seven categories.
  • Discrete-time survival models adjusted for demographics, BMI, and comorbidities, with stratified analyses for cardiovascular and chronic kidney disease.

Main Results:

  • The lowest all-cause mortality risk was observed in Veterans with systolic BP between 130-139 mmHg.
  • Compared to a systolic BP ≥160 mmHg, adjusted hazard ratios for mortality were lower across all analyzed BP categories below 160 mmHg.
  • These associations remained consistent across subgroups with cardiovascular disease and chronic kidney disease.

Conclusions:

  • Routine systolic blood pressure of 130-139 mmHg was associated with the lowest mortality in US Veterans.
  • Findings suggest that a higher BP target might be more appropriate in clinical practice for certain populations, especially older adults with comorbidities.
  • This study highlights the importance of considering real-world BP measurements and patient-specific factors in hypertension management.