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Updated: Apr 8, 2026

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
Beyond age: Frailty-guided care in hematologic malignancies
Reed Friend1, P Connor Johnson2, Daphne Campbell3
1Division of Hematology, Atrium Health Levine Cancer Institute, Wake Forest University School of Medicine, Charlotte, North Carolina, USA.
Abstract:
Frailty, distinct from chronological age, reflects physiologic reserve and predicts toxicity, treatment discontinuation, and survival across hematologic malignancies. The authors synthesize contemporary frailty tools and summarize disease-specific evidence in multiple myeloma, acute myeloid leukemia, and aggressive lymphomas. Integrating frailty measures can inform shared decision-making and guide the management of vulnerable populations to enhance therapeutic benefit and optimize quality of life.
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