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Refined CLARITY-Based Tissue Clearing for Three-Dimensional Fibroblast Organization in Healthy and Injured Mouse Hearts
Published on: May 16, 2021
Fibroblast Activation Targeted Imaging Identifies Coronary Restenosis
Xiao-Ying Xi1, Shengwen Yang2, Bin Tu2
1Department of Nuclear Medicine.
None:
A 49-year-old woman with chronic total occlusion of the proximal left anterior descending (LAD) artery underwent a baseline 18 F-FAPI PET/CT, and showed no abnormal uptake in the coronary artery. New focal 18 F-FAPI activity appeared at the LAD stent ostium at 6 months and progressed by 1 year, preceding angiographically confirmed in-stent restenosis. This case demonstrates that 18 F-FAPI imaging may detect early fibro-inflammatory activity predictive of restenosis.
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