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Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
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Comparison of Visual Performance Among Two Multifocal-Extended Depth-of-Focus Intraocular Lens Types and a Trifocal

Ken Hayashi, Koichi Uno, Shunsuke Hayashi

    Journal of Refractive Surgery (Thorofare, N.J. : 1995)
    |April 7, 2026
    PubMed
    Summary
    This summary is machine-generated.

    The new TECNIS Odyssey intraocular lens (IOL) offers improved uncorrected far and intermediate vision compared to other multifocal IOLs. However, it shows reduced near vision, suggesting a far-dominant visual profile.

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    Area of Science:

    • Ophthalmology
    • Biomedical Engineering
    • Optics

    Background:

    • Intraocular lenses (IOLs) are crucial for vision restoration after cataract surgery.
    • Multifocal and extended depth-of-focus (EDOF) IOLs aim to provide spectacle independence by correcting vision at multiple distances.
    • Continuous innovation in IOL technology seeks to optimize visual performance and patient satisfaction.

    Purpose of the Study:

    • To compare the visual performance of the new TECNIS Odyssey multifocal-EDOF IOL.
    • To evaluate its visual outcomes against an earlier multifocal-EDOF IOL (TECNIS Synergy) and a trifocal IOL (PanOptix).

    Main Methods:

    • Ninety eyes of 90 patients were implanted with one of three IOL types.
    • Visual acuity (uncorrected and corrected) at various distances was assessed.
    • Photopic and mesopic contrast visual acuity and photic symptoms were evaluated 3 months postoperatively.

    Main Results:

    • The TECNIS Odyssey group showed better uncorrected far and intermediate visual acuity (infinity to 1m) than other groups (P <= .046).
    • However, uncorrected near visual acuity (0.3m) and intermediate visual acuity (0.5m) were worse in the Odyssey group (P <= .028).
    • Mesopic contrast visual acuity and glare tolerance were significantly better with the Odyssey IOL (P <= .040).

    Conclusions:

    • The TECNIS Odyssey IOL demonstrates superior uncorrected far and intermediate vision compared to the Synergy and PanOptix IOLs.
    • It exhibits a far-dominant visual profile with potential for greater tolerance to refractive errors.
    • Trade-offs include reduced near and intermediate visual acuity, necessitating careful patient selection.