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Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
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EasyREG: Easy Depth-Based Markerless Registration and Tracking using Augmented Reality Device for Surgical Guidance.

Yue Yang, Christoph Leuze, Brian Hargreaves

    IEEE Transactions on Visualization and Computer Graphics
    |April 7, 2026
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a novel markerless surgical guidance framework using Augmented Reality (AR) depth sensors. It achieves accurate, real-time patient anatomy tracking without cumbersome markers, enhancing surgical navigation.

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    Area of Science:

    • Medical Technology
    • Computer-Aided Surgery
    • Augmented Reality

    Background:

    • Traditional surgical guidance relies on fiducial markers, posing clinical challenges.
    • Existing markerless AR solutions struggle with accuracy due to occlusions and sensor data outliers.

    Purpose of the Study:

    • To develop a robust, markerless framework for precise surgical guidance using AR devices.
    • To overcome limitations of current marker-based and markerless tracking systems in medical applications.

    Main Methods:

    • A two-module system: registration for accurate anatomy localization and tracking for real-time pose estimation.
    • Utilizes AR depth sensors, depth error correction, human-in-the-loop filtering, and curvature-aware feature sampling.
    • Incorporates Iterative Closest Point (ICP) refinement for precise alignment.

    Main Results:

    • The markerless system demonstrates superior registration accuracy compared to industrial solutions.
    • Tracking performance is comparable to existing commercial systems.
    • The framework effectively handles both static and moving target anatomy.

    Conclusions:

    • The proposed markerless framework offers a high-precision, outlier-robust solution for surgical guidance.
    • It provides a comprehensive, one-stop system for diverse surgical scenarios.
    • This technology has the potential to improve the safety and efficiency of AR-assisted surgery.