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Telehealth Delivery of the Homeostasis-Enrichment-Plasticity Approach for Premature Infants With Developmental Risks:
Aymen Balikci1, Gamze Cagla Sirma2, Izgi-Miray Demirbag1
1Sense On Ltd, Istanbul, Turkey.
Journal of Medical Internet Research
|April 7, 2026
Summary
Telehealth delivery of the Homeostasis-Enrichment-Plasticity (HEP) Approach proved feasible and safe for preterm infants, showing positive developmental and psychosocial outcomes. This family-centered model offers a promising accessible intervention for high-risk infants.
Area of Science:
- Developmental Pediatrics
- Telehealth Interventions
- Neuroplasticity Research
Background:
- Preterm delivery presents significant neurodevelopmental risks, necessitating early intervention.
- Logistical and financial barriers often limit access to crucial early intervention services.
- The Homeostasis-Enrichment-Plasticity (HEP) Approach is a family-centered model promoting infant development through enriched environments.
Purpose of the Study:
- To evaluate the feasibility, safety, and acceptability of the HEP Approach delivered via telehealth.
- To assess the sensitivity to change of developmental outcomes using the HEP Approach in preterm infants.
- To determine the effectiveness of a telehealth-based family-centered early intervention for at-risk premature infants.
Main Methods:
- A pre-post exploratory feasibility study involving 16 preterm infants (4-12 months corrected age).
- A 12-week intervention with weekly remote sessions focusing on enrichment, exploration, and parental guidance.
- Feasibility and acceptability assessed via questionnaire; developmental outcomes measured using standardized tools (YCPEM, ASQ, AIMS, IMP, DASS).
Main Results:
- High adherence (100%) and retention (87.5%) confirmed robust feasibility.
- Parents reported high satisfaction (86%-100%), affirming safety and acceptability with no adverse events.
- Significant improvements observed in infant participation, motor skills, communication, socio-emotional domains, and caregiver well-being (P<.05).
Conclusions:
- Telehealth implementation of the HEP Approach is feasible, safe, and well-accepted by families of preterm infants.
- The intervention demonstrated positive impacts on infant development and caregiver psychosocial status.
- Findings support the HEP Approach via telehealth as a viable, accessible framework, warranting further validation through RCTs.
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