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Related Concept Videos

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Predictors of Breath Alcohol Profiles: A Multiple-Study Lab-Based Approach.

Derek D Morgan1, Keely A Dugan1, Shuo Yan1

  • 1Department of Psychological Sciences, University of Missouri, Columbia, Missouri, USA.

Alcohol, Clinical & Experimental Research
|April 8, 2026
PubMed
Summary
This summary is machine-generated.

Breath alcohol content (BrAC) profiles in emerging adults show three distinct patterns following alcohol consumption. Physical characteristics like BMI and body water influence these alcohol response trajectories.

Keywords:
alcohol administrationbreath alcohol contentdrinkingrepeated measure latent profile analysis

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Area of Science:

  • Pharmacology and Toxicology
  • Human Physiology
  • Behavioral Science

Background:

  • Oral alcohol administration studies reveal varied breath alcohol content (BrAC) levels.
  • Distinct BrAC trajectories and their predictors remain underexplored.

Purpose of the Study:

  • To identify and characterize distinct breath alcohol content (BrAC) profiles.
  • To investigate predictors of these BrAC profiles in emerging adults.

Main Methods:

  • Two laboratory studies administered alcohol to emerging adults targeting 0.08% and 0.10% blood alcohol concentrations (BAC).
  • Breath alcohol content (BrAC) was measured every 15 minutes for seven intervals.
  • Repeated measure latent profile analysis (RMLPA) identified BrAC profiles, with individual characteristics examined as predictors.

Main Results:

  • A three-profile solution (high-fast, moderate, low-slow risers) was consistent across both BAC levels.
  • Profile membership was predicted by body mass index, total body water, and individual alcohol response.

Conclusions:

  • Emerging adults exhibit three primary BrAC profiles during laboratory alcohol administration.
  • Physical characteristics and alcohol response are key differentiators of these BAC profiles.