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Predictors of Breath Alcohol Profiles: A Multiple-Study Lab-Based Approach
Derek D Morgan1, Keely A Dugan1, Shuo Yan1
1Department of Psychological Sciences, University of Missouri, Columbia, Missouri, USA.
Alcohol, Clinical & Experimental Research
|April 8, 2026
Summary
Breath alcohol content (BrAC) profiles in emerging adults show three distinct patterns following alcohol consumption. Physical characteristics like BMI and body water influence these alcohol response trajectories.
Area of Science:
- Pharmacology and Toxicology
- Human Physiology
- Behavioral Science
Background:
- Oral alcohol administration studies reveal varied breath alcohol content (BrAC) levels.
- Distinct BrAC trajectories and their predictors remain underexplored.
Purpose of the Study:
- To identify and characterize distinct breath alcohol content (BrAC) profiles.
- To investigate predictors of these BrAC profiles in emerging adults.
Main Methods:
- Two laboratory studies administered alcohol to emerging adults targeting 0.08% and 0.10% blood alcohol concentrations (BAC).
- Breath alcohol content (BrAC) was measured every 15 minutes for seven intervals.
- Repeated measure latent profile analysis (RMLPA) identified BrAC profiles, with individual characteristics examined as predictors.
Main Results:
- A three-profile solution (high-fast, moderate, low-slow risers) was consistent across both BAC levels.
- Profile membership was predicted by body mass index, total body water, and individual alcohol response.
Conclusions:
- Emerging adults exhibit three primary BrAC profiles during laboratory alcohol administration.
- Physical characteristics and alcohol response are key differentiators of these BAC profiles.
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