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Prediction of adverse events in proximal interphalangeal joint surface-replacement implants
Elisa Hornung1, Kei H Mathis1, Miriam Marks1
1Department of Teaching, Research and Development, Schulthess Klinik, Switzerland.
The Journal of Hand Surgery, European Volume
|April 8, 2026
Summary
Greater surgical experience in proximal interphalangeal joint (PIPJ) surface replacement reduces implant revision risk. However, factors beyond surgical experience influence adverse events after PIPJ arthroplasty.
Area of Science:
- Orthopedic surgery
- Biomaterials science
- Hand surgery
Background:
- Proximal interphalangeal joint (PIPJ) surface replacement aims to restore function and reduce pain.
- Adverse events and implant revision are significant concerns following PIPJ arthroplasty.
- Predictors of long-term outcomes after PIPJ surface replacement require further investigation.
Purpose of the Study:
- To identify predictors of adverse events and implant revision risk up to 10 years after PIPJ surface replacement.
- To analyze the impact of patient, surgical, and implant factors on PIPJ arthroplasty outcomes.
Main Methods:
- Registry-based analysis of 476 CapFlex-PIP prostheses implanted between 2010 and 2024.
- Logistic regression models used to assess predictors of limited range of motion, implant problems, and revision surgery.
- Covariates included sociodemographic data, clinical measures, patient-reported outcomes, and surgical details.
Main Results:
- Younger age and prior hand surgeries correlated with reduced range of motion.
- The little finger showed a higher risk of implant-related problems.
- Increased surgical experience significantly reduced implant-related problems (83%) and revision surgery (76%).
Conclusions:
- Greater surgical experience is a key factor in minimizing adverse events and revision needs after PIPJ surface replacement.
- While surgical experience is important, it explains only a small portion of adverse event variance, indicating other contributing factors.
- Further research is needed to elucidate the multifactorial nature of adverse events in PIPJ arthroplasty.

