Related Experiment Video
Updated: Apr 9, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Post-POEM Esophageal Leak Successfully Managed With Endoscopic Vacuum Therapy
Mohamed Elshennawy1, Sultan Mahmood2
1Gastroenterology and Hepatology Department, Theodor Bilharz Research Institute, Cairo, Egypt.
Persistent esophageal leaks after peroral endoscopic myotomy (POEM) can be challenging. Endoscopic vacuum therapy (EVT, EndoVAC) offers a novel solution for managing these difficult mucosal defects when conventional methods fail.
Area of Science:
- Gastroenterology
- Minimally Invasive Surgery
- Endoscopy
Background:
- Esophageal leaks are known complications following peroral endoscopic myotomy (POEM).
- Current endoscopic techniques for managing mucosal defects after POEM have variable success rates.
- Persistent leaks pose significant management challenges.
Related Concept Videos
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...

