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Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications
Published on: April 28, 2015
Magnetic borylated conjugated polymer nanoparticles for deep-red optical and lifetime imaging
Struan Bourke1, Yurema Teijeiro Gonzalez1, Patrick Bergstrom Mann1
1Department of Physics, King's College London, Strand Campus, London WC2R 2LS, UK. mark.a.green@kcl.ac.uk.
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The near-IR emitting conjugated polymer (borylated poly(9,9-dioctylfluorene-alt-benzothiadiazole)) was processed into colloidally stable nanoparticles doped with superparamagnetic iron oxide nanoparticles (SPIONs), giving multifunctional luminescent and magnetic nanoparticles between 100-120 nm in diameter. Emission between 710 and 720 nm was observed, and quantum yields (QYs) of up to 2.7% were achieved. The resulting particles were used to image HeLa cells using conventional and lifetime imaging techniques.

