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Preoperative MRI-Derived Navigation Reduces Radiation Exposure in Pediatric Spinal Fusion
Stefano Cardin1, Logan A Reed, Kivanc Atesok
1Division of Pediatric Orthopaedics, Orlando Health Arnold Palmer Hospital for Children, Orlando, FL.
Journal of Pediatric Orthopedics
|April 8, 2026
Summary
Minimizing radiation in pediatric spinal surgery is crucial. Using MRI-derived synthetic CT data for navigation significantly reduces radiation exposure compared to traditional methods, offering a safer alternative for adolescent idiopathic scoliosis treatment.
Area of Science:
- Orthopedic Surgery
- Medical Imaging
- Radiation Oncology
Background:
- Minimizing cumulative radiation exposure in pediatric spinal deformity correction is vital.
- Ionizing radiation poses long-term health risks for children.
- This study explores reducing radiation by eliminating preoperative CT scans using MRI-derived synthetic CT data.
Purpose of the Study:
- To evaluate the efficacy of MRI-to-synthetic CT navigation in reducing radiation exposure during spinal fusion for adolescent idiopathic scoliosis (AIS).
- To compare radiation doses and surgical parameters between fluoroscopy-only, CT-based navigation, and MRI-to-CT navigation.
Main Methods:
- Retrospective comparative study of 94 pediatric patients undergoing posterior spinal fusion for AIS.
- Three groups: fluoroscopy-only, CT-based navigation, and MRI-to-CT navigation.
- Machine learning models converted MRI signals to CT Hounsfield units for registration.
Main Results:
- Both navigation groups significantly reduced intraoperative fluoroscopy time and effective radiation dose compared to fluoroscopy-only.
- MRI-to-CT navigation achieved radiation profiles comparable to CT-based navigation.
- The MRI-to-CT group eliminated the need for preoperative CT scans, significantly reducing overall radiation exposure.
Conclusions:
- MRI-to-synthetic CT navigation is a safe and effective radiation-sparing alternative for pedicle screw placement in pediatric deformity surgery.
- This technique offers comparable intraoperative radiation profiles to CT-based navigation without requiring a preoperative CT.
- Reducing radiation load is critical for long-term pediatric patient outcomes.

