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Related Experiment Video

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BiFUSE-UNet: a novel dual-encoder enhanced TransUNet for polyp segmentation.

Wenli Lei1,2, Tianwu Yao1,2, Rui Feng1

  • 1Yan'an University, Yan'an, Shaanxi 716000, People's Republic of China.

Biomedical Physics & Engineering Express
|April 8, 2026
PubMed
Summary

Accurate polyp segmentation in medical images is crucial for early cancer detection. BiFuse-UNet, a novel dual-encoder TransUNet, significantly improves polyp segmentation accuracy, outperforming existing methods.

Keywords:
BiFormerMaxViTTransUNetmedical image segmentationpolyp segmentation

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Area of Science:

  • Medical Imaging
  • Computer Vision
  • Artificial Intelligence

Background:

  • Polyps are abnormal mucosal tissue growths with potential for malignant transformation.
  • Accurate segmentation of polyps in medical images is challenging due to morphological heterogeneity, blurry boundaries, and data limitations.
  • Early detection and intervention for polyps can prevent malignant progression.

Purpose of the Study:

  • To develop an advanced deep learning model for accurate polyp segmentation in medical images.
  • To address the challenges of polyp segmentation, including appearance variability and boundary ambiguity.
  • To improve the detection of subtle and early-stage polyps with atypical morphology.

Main Methods:

  • Introduction of BiFuse-UNet, a novel dual-encoder TransUNet architecture with a bidirectional fusion mechanism.
  • Integration of a multi-axis attention module (MaxViT block) for multi-scale feature extraction and long-range dependency capture.
  • Incorporation of a Merge fusion module with Coordinate Attention and SaE block for enhanced local feature perception.
  • Utilization of a Biformer module to balance global semantics and local details for improved segmentation.

Main Results:

  • BiFuse-UNet achieved state-of-the-art segmentation performance on the Kvasir-SEG dataset.
  • The model outperformed seven existing methods in Dice coefficient, Recall, Precision, and IoU metrics.
  • BiFuse-UNet effectively handled morphological heterogeneity, blurry boundaries, and background interference.

Conclusions:

  • BiFuse-UNet demonstrates superior accuracy in pixel-level polyp segmentation.
  • The proposed architecture offers a robust solution for challenging polyp segmentation tasks.
  • This advancement contributes to more reliable early detection and diagnosis of polyps.