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Integrated histomolecular diagnosis of mesenteric anisakiasis

Emilie Kariya1, Pauline Tirard-Collet2,3, Camille Boulagnon-Rombi4

  • 1UR ESCAPE, Parasitology-Mycology Laboratory, Biology and Pathology Department, Reims University Hospital, University of Reims Champagne-Ardenne, Reims, France ekariya@chu-reims.fr.

Journal of Clinical Pathology
|April 8, 2026
PubMed

A 49-year-old woman was admitted with gastrointestinal symptoms and imaging consistent with duodeno-ileitis. Her clinical course was complicated by mesenteric ischaemia, requiring resection of a 45-cm ileal segment. A pre-adult Anisakis spp. larva was identified within a mesenteric nodule through an innovative diagnostic approach combining histopathological analysis with shotgun metagenomic analysis.

Keywords:
Gastrointestinal DiseasesHistologyPARASITESPathology, Molecular

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