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Bowel Habits and Functional Constipation in Healthy Children-A Longitudinal Birth-Cohort Study
C Gatzinsky1,2, U Sillén1,2, M Bräutigam1,2
1Institute of Clinical Sciences, Department of Paediatrics, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.
Insights
Functional constipation affects one-fifth of young children, often requiring long-term medication and follow-up. Breastfeeding in early infancy may reduce the risk of functional constipation.
Area of Science:
- Pediatric Gastroenterology
- Child Health Outcomes
Background:
- Functional constipation (FC) is a prevalent concern in pediatric healthcare.
- Parental anxiety regarding infant bowel habits frequently leads to medical consultations.
Purpose of the Study:
- To establish normative data for infant bowel habits.
- To determine the prevalence and long-term outcomes of FC in early childhood.
- To identify potential risk factors for FC development.
Main Methods:
- Prospective longitudinal birth-cohort study.
- Inclusion of 122 healthy term infants.
- Repeated parental questionnaire assessments.
Main Results:
- Stool frequency normalized by 6 months; stool consistency hardened with age.
- Prevalence of FC was 22.1%; 69.6% required ongoing medication.
- Relapse occurred in 26.1% of cases.
- Early breastfeeding (2 weeks) was associated with reduced FC risk.
Conclusions:
- One-fifth of children develop FC within the first 2.5 years.
- FC often requires prolonged treatment, frequent medical visits, and sustained follow-up due to high relapse rates.
Aim:
Functional constipation is common during childhood. Parents' concerns about their child's bowel habits are often the reason for seeking healthcare. We aim to report data on normal bowel habits, prevalence of functional constipation, long-term outcome, and a search for risk factors in children during the first 2.5 years of life.
Methods:
This prospective longitudinal birth-cohort study included 122 healthy term infants, and repeated questionnaires were answered by parents.
Result:
Stool frequency declined with age and stabilised after 6 months. Stool consistencies changed, with hard and very hard stools increasing with age. Functional constipation was found in 22.1%, and at the last follow-up, 69.6% were still on medication. Relapse was seen in 26.1% on follow-up. Risk factors at baseline or at 2 months of age that increased the odds of having functional constipation thereafter were not found. Breastfeeding at 2 weeks decreased the probability of FC in the first 2.5 years of life.
Conclusion:
We report data on normal bowel habits from birth to 2.5 years of age. One fifth of the children were diagnosed with functional constipation, and relapse was common; therefore, endurance of treatment, repeated visits, and long-term follow-up are necessary since many children need medication for several years.
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