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Updated: Apr 10, 2026

An Improved Method for the Preparation of Type I Collagen From Skin
Published on: January 21, 2014
Oral Fish Collagen Peptide Complex Enhances Skin Rejuvenation and Systemic Health Biomarkers: A 90 Day Prospective
Jingjing Huang1,2, Chao Chen3,4, Meng Zhang1,2
1School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing, China.
Fish Collagen Peptide Nutritional Combination (FCPNC) improved facial skin hydration, elasticity, and reduced wrinkles. It also offered systemic benefits like normalizing BMI and increasing antioxidant capacity, suggesting potential as a functional food.
Area of Science:
- Nutritional Science
- Dermatology
- Biochemistry
Background:
- Aging skin presents challenges in maintaining hydration, elasticity, and wrinkle reduction.
- Systemic health indicators such as Body Mass Index (BMI), blood lipids, and bone mineral density are crucial for overall well-being.
- Superoxide Dismutase (SOD) plays a vital role in cellular antioxidant defense.
Purpose of the Study:
- To investigate the efficacy of Fish Collagen Peptide Nutritional Combination (FCPNC) for facial skin rejuvenation.
- To assess the impact of FCPNC on biochemical indicators including BMI, blood lipids, SOD, and bone mineral density.
- To evaluate participant satisfaction with FCPNC for skin, nail, and hair health.
Main Methods:
- A 90-day intervention study involving 29 female participants (aged 20-55) consuming FCPNC daily.
- Assessment of facial skin parameters (wrinkle percentage, pigmentation, hydration, elasticity) pre- and post-intervention.
- Measurement of BMI, blood tests (including SOD and calcium levels), and bone mineral density at baseline and study conclusion.
Main Results:
- Significant improvements observed in skin hydration, elasticity, and reduced wrinkle area percentage after 30, 60, and 90 days.
- Systemic benefits included BMI normalization in 58.33% of overweight participants and a 31.03% increase in SOD activity.
- Calcium levels increased by 48.28%, indicating potential bone health advantages, with 93% participant satisfaction by study end.
Conclusions:
- FCPNC demonstrates potential benefits for both skin health and overall physiological status.
- The findings support the consideration of FCPNC as a functional food for health and wellness.
- Further large-scale randomized controlled trials are recommended to substantiate these preliminary results.
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