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Updated: Apr 10, 2026

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Safe Proton Beam Re-irradiation With a Bioabsorbable Spacer in Pancreatic Cancer: A Case Report
Shintaro Shiba1, Koichi Tokuuye1, Kazuya Koizumi2,3
1Department of Radiation Oncology, Shonan Kamakura General Hospital, 1370-1, Okamoto, Kamakura, Kanagawa 247-8533, Japan.
International Journal of Particle Therapy
|April 9, 2026
Summary
Proton beam therapy re-irradiation for pancreatic cancer is feasible using bioabsorbable polyglycolic acid (PGA) spacers to protect the stomach. This technique safely delivered radiation, controlled the cancer, and showed no adverse events.
Area of Science:
- Radiation Oncology
- Medical Physics
- Gastroenterology
Background:
- Proton beam therapy (PBT) re-irradiation for pancreatic cancer is limited by dose constraints in adjacent gastrointestinal organs.
- Bioabsorbable polyglycolic acid (PGA) spacers offer a potential solution to mitigate radiation exposure to nearby organs.

