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High dose fish oil lipid emulsion (FOLE) use in pediatric patients: A case series

Sean Coyne1, Uyen Le2, Margaret Murphy1

  • 1Boston Children's Hospital, Boston, MA, USA.

Intestinal Failure (New York, N.Y.)
|April 9, 2026
PubMed

Insights

Higher doses of fish oil-based lipid emulsion (FOLE) safely support pediatric patients with intestinal failure-associated liver disease (IFALD), enabling longer parenteral nutrition (PN) cycles and promoting growth.

Area of Science:

  • Pediatric Gastroenterology
  • Hepatology
  • Parenteral Nutrition

Background:

  • Intestinal Failure-Associated Liver Disease (IFALD) poses challenges for pediatric patients requiring long-term parenteral nutrition (PN).
  • Current PN formulations may not fully address the metabolic and hepatic complications associated with IFALD.

Keywords:
ILFADIntravenous lipid emulsionParenteral nutritionPediatric

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