Related Experiment Video
Updated: Apr 10, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
Published on: June 15, 2011
Change in movement disorder specialist attitudes to genetic testing after implementation of PD GENEration
Jesse Wang1, Vanessa Ibrahim1, Julian Agin-Liebes2
1Department of Neurology, Mass General Brigham, Boston, MA.
Purpose:
Despite advances in recent years, genetic testing for Parkinson disease (PD) is still underutilized in clinical practice. A 2019 questionnaire of movement disorder specialists found low rates of genetic testing in PD and barriers such as cost and insurance coverage. Since that time, PD GENEration, as well as several international programs, have broadly increased access to genetic testing and counseling for people with PD. A repeat survey sent out in 2024 examined how attitudes to genetic testing for PD in clinical practice have changed over the past 5 years.
Methods:
Between October 2024-January 2025, 621 movement disorders specialists from the Parkinson's Study Group (PSG) were invited by email to complete a questionnaire assessing knowledge, attitudes, and barriers to genetic testing in PD based on the 2019 survey.
Results:
In total, 119 PSG clinicians from the United States and Canada responded to the questionnaire. When compared with results from 2019, in 2024 both PD GENEration-affiliated and nonaffilated survey respondents reported fewer barriers to genetic testing both at the clinician and patient level.
Conclusion:
2024 survey respondents report greater comfort with ordering and returning genetic test results compared with 2019, concurrent with the launch of PD GENEration, ROPAD, and GP2.
More Related Videos
Related Concept Videos
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
Genetic Screens
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
Pharmacogenomics: Identification of New Drug Targets
What is Genetic Engineering?
Behavioral Genetics and Its Designs
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
Gene Therapy

