Vogt-Koyanagi-Harada Disease with Oral Manifestations: A Rare Case Report

Vogt-Koyanagi-Harada disease (VKHD) is a rare, autoimmune multisystem inflammatory disorder of unknown etiology affecting melanocyte-containing tissues such as eyes, ears, skin, and central nervous system. Hallmark features of VKHD are rapid vision loss, uveitis, hearing loss, alopecia, and skin depigmentation. Ocular and systemic manifestations of VKHD are well-documented; the involvement of the oral cavity remains exceedingly rare. We report a rare case of VKHD in a 21-year-old Asian female presenting with discoloured and misaligned teeth. Vitiligo and alopecia patches with a short upper lip were noticed. Maxillary incisors were proclined, mandibular incisors were retroclined, nasolabial angle was obliterated; and maxillary arch was V-shaped with a deep palatal vault. Yellow-brown discoloration with altered cuspal morphology was observed in all teeth. This case report expands the clinical spectrum of VKHD associated with oral manifestations. It is important for the clinicians to recognize atypical presentations for comprehensive management.