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Preendodontic Dentin Hybridization - Effect on Coronal Dentin Microhardness and Resin-Dentin Bond Strength: An In
Gonapa Prasanthi1, Duvvuri Lakshmi Malini1, B Devipriya1
1Department of Conservative Dentistry and Endodontics, Government Dental College and Hospital, Vijayawada, Andhra Pradesh, India.
Contemporary Clinical Dentistry
|April 9, 2026
Summary
Pre-endodontic dentin hybridization (PEDH) shields coronal dentin from endodontic chemicals, preserving microhardness and bond strength. This protective method maintains dentin properties effectively, similar to untreated controls.
Area of Science:
- Dental Materials Science
- Endodontics
- Biomaterials
Background:
- Endodontic chemical substances (ECS) can compromise coronal dentin integrity.
- This structural impact can negatively affect the success of endodontic therapy.
- Pre-endodontic dentin hybridization (PEDH) is proposed as a protective strategy.
Purpose of the Study:
- To evaluate the impact of ECS on dentin microhardness and resin-dentin microshear bond strength (µSBS).
- To assess the protective efficacy of PEDH against ECS-induced degradation.
- To compare different hybridization timings and ultrasonic repreparation effects.
Main Methods:
- Eighty dentin specimens were divided into Control, Late Dentin Hybridization (LDH), PEDH, and Ultrasonic LDH (ULDH) groups.
- Specimens were exposed to ECS, followed by or preceded by dentin hybridization.
- Microhardness and µSBS were measured using Vickers micro indenter and universal testing machine, respectively.
Main Results:
- LDH significantly reduced bond strength compared to all other groups.
- The PEDH group demonstrated microhardness and µSBS values comparable to the control group.
- ULDH improved bond strength over LDH but significantly decreased microhardness.
Conclusions:
- ECS exposure detrimentally affects coronal dentin microhardness and µSBS.
- PEDH effectively preserves dentin properties, yielding results similar to untreated controls.
- PEDH offers a protective benefit without requiring additional ultrasonic procedures.

