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Related Concept Videos

Regulation of Angiogenesis and Blood Supply01:24

Regulation of Angiogenesis and Blood Supply

Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl hydroxylase and factor...

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A Novel Mammary Fat Pad Transplantation Technique to Visualize the Vessel Generation of Vascular Endothelial Stem Cells
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VE-Cadherin Dual Reporter Mouse Lines for Studying Endothelial Functions

Lu Zhang1, Jun Chen2,3, Hao Peng1

  • 1Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, China (L.Z., H.P., X.L., X.W., W.M., W.R., X.Y., J.X., C.-L.C.).

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No abstract available in PubMed .

Keywords:
cadherin 5endothelial cellsgreen fluorescent proteinssingle-cell gene expression analysistdTomato

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