Chiral discrimination on gate-based quantum computers

We present a novel approach to chiral discrimination using gate-based quantum processors, addressing a key challenge in adapting conventional control techniques using modern quantum computing. Schemes such as stimulated rapid adiabatic passage and shortcuts to adiabaticity have shown strong potential for enantiomer discrimination; however, their reliance on analog and continuous-time control makes them incompatible with digital gate-based quantum computing architectures. Here, we adapt these protocols for quantum computers by discretizing their Gaussian-shaped pulses through Trotterization. We simulate the chiral molecule 1,2-propanediol and experimentally validate this gate-based implementation on IBM quantum hardware. Our results demonstrate that this approach is a viable foundation for advancing chiral discrimination protocols, preparing the way for quantum-level manipulation of molecular chirality on accessible quantum architectures.