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Updated: Apr 10, 2026

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
Standardisation of histologic reporting in eosinophilic oesophagitis: Expert recommendations
Carla Giordano1, Valentina Angerilli2, Marco Masci1
1Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy.
None:
Over the past decade, significant progress has been made in understanding eosinophilic oesophagitis (EoE), leading to the refinement of diagnostic criteria and the development of evidence-based management guidelines. Nevertheless, despite the central role of histology in both diagnosis and disease monitoring, significant variability remains in histopathological reporting across institutions and among pathologists.This study seeks to provide recommendations for standardised histological reporting in EoE. To this end, a multidisciplinary panel of gastroenterologists and pathologists convened to review current practices and address persistent challenges in histologic assessment. Through an extensive literature review and critical appraisal of existing scoring systems, the panel reached consensus on both essential and desirable histological features for routine reporting, including eosinophil counts, additional inflammatory parameters, and fibrostenotic changes.
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