Related Experiment Video
Updated: Jul 9, 2026

Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models
Published on: January 5, 2024
A splanchnic venous thrombosis revealing Biermer's disease: a case report
Abdelghani Bachir Cherif1, Salam Bennouar2, Sara Benzaamia3
1Internal Medicine Department, University Hospital of Blida, University of Blida 1, Bilda, Algeria. ghani11bc@yahoo.fr.
Abstract:
Biermer's disease, or pernicious anemia, is an autoimmune condition marked by vitamin B12 deficiency due to intrinsic factor antibodies targeting gastric parietal cells. The relationship between Biermer's disease and increased thrombotic risk, while uncommon, represents a critical clinical concern necessitating heightened diagnostic awareness for patients presenting with unexplained thrombotic symptoms. This report details the case of a 57-year-old Mediterranean male, with a prior diagnosis of Graves' disease, who developed splanchnic venous thrombosis. An extensive etiological investigation revealed mild hyperhomocysteinemia, associated with an undiagnosed Biermer's disease. Our case underscores a critical association between Biermer's disease, hyperhomocysteinemia, and venous thrombosis, emphasizing the imperative for further research elucidating their interconnected pathogenesis.
Related Concept Videos
Esophageal Varices-I: Introduction
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Endocarditis II: Clinical Features of Infective Endocarditis
Venous Thrombosis I: Introduction
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Portal Hypertension

