Related Experiment Video
Updated: Apr 10, 2026

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
Published on: February 17, 2023
Campylobacter jejuni bacteremia in a neutropenic child with B-Cell acute lymphoblastic leukemia
Koray Bakır1, Onur Mert Çelik2, Gizem Korkut3
1Department of Pediatric Infectious Diseases, Ankara Etlik City Hospital, Ankara, Turkey. korayf1@gmail.com.
Insights
A rare case of Campylobacter jejuni bacteremia in a child with B-cell acute lymphoblastic leukemia (B-ALL) during neutropenia highlights the need for prompt diagnosis and treatment. Targeted antibiotics led to full recovery, emphasizing effective antimicrobial management in immunocompromised patients.
Area of Science:
- Pediatric Oncology
- Infectious Diseases
- Hematology
Background:
- Campylobacter jejuni bacteremia is uncommon in children, particularly those with B-cell acute lymphoblastic leukemia (B-ALL).
- Chemotherapy-induced neutropenia significantly increases the risk of severe infections in pediatric cancer patients.
Abstract:
We describe a rare case of Campylobacter jejuni bacteremia in a 4-year-old girl with B-cell acute lymphoblastic leukemia (B-ALL) carrying the t(12;21) translocation. The infection occurred during chemotherapy-induced neutropenia and presented with fever and diarrhea. Blood and port cultures identified C. jejuni, and targeted antibiotic therapy with meropenem, azithromycin, and gentamicin resulted in full recovery. This case adds to the limited reports of C. jejuni bacteremia in children with B-ALL and underscores the importance of prompt diagnosis and appropriate antimicrobial management in immunocompromised hosts.
Related Concept Videos
Bacterial Gastroenteritis
Disorders of Leukocytes
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Pyelonephritis I: Introduction
Bacterial Translocation and Protein Secretion
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...

