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Perforated Mooren's ulcer in African melanoderm: Report of 18 cases
A K J Konan1, Y G Ouffoue1, O A S Ouattara1
1Department of Ophthalmology Treichville University Hospital/Felix Houphouët Boigny University, Abidjan, Ivory Coast.
Introduction:
Corneal perforation is a progressive complication of Mooren's ulcer. Its management in African blacks is difficult and empirical.
Materials And Methods:
We performed a prospective study over a 6-year period on black African patients with perforated Mooren's ulcers. They received medical and surgical treatment.
Results:
Eighteen eyes of sixteen patients were included during the study period. The mean age was 29.54years with a sex ratio of 0.6. Six eyes were visually impaired, while ten eyes (55.6%) were blind. Corneal suturing combined with conjunctival advancement was performed in 72.2% of cases, and an amniotic membrane graft was used in 27.8%. Recurrence after treatment was observed in 33.3% of cases. In univariate analysis, predictive factors for recurrence include female gender, age under 30, and a delay until consultation of more than 3 months.
Conclusion:
Perforated Mooren's ulcer is a blinding disease in African blacks. Recurrence is frequent and requires special attention from the patient and the specialist. Amniotic membrane transplantation has proven to be an effective treatment.
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