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Updated: Apr 11, 2026
Mouse Fetal Liver Culture System to Dissect Target Gene Functions at the Early and Late Stages of Terminal Erythropoiesis
Published on: September 9, 2014
A sharper view: Imaging the fetal liver niche for HSCs
Niveda Udaykumar1, Shannon L McKinney-Freeman1
1Department of Hematology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.
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In this issue of Developmental Cell, Vijaykumar et al. interrogate the fetal liver (FL) hematopoietic stem and progenitor cell (HSPC) niche using 3D quantitative microscopy, fluorescent genetic reporters, and transcriptomics, thereby illuminating important HSPC support cells and mechanisms impacting HSPC FL egress across this window of ontogeny.1.
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