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Updated: Apr 11, 2026

Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion
Published on: January 15, 2016
Effect of Q-angle symmetry on knee joint kinematics in level walking, upslope walking and landing task
Zibo Gao1,2, Qingyang Kang1,2, Yang Liu1,2
1The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong, China.
Background:
The quadriceps angle (Q-angle) is a key biomechanical measure of lower limb alignment. While its asymmetry is linked to knee disorders like patellofemoral pain, its dynamic impact on full six-degree-of-freedom (6DOF) knee kinematics across different tasks remains unclear.
Methods:
Forty healthy university students were categorized into Q-angle symmetric (QS, bilateral difference ≤ 3°) or asymmetric (QA, > 3°) groups. Knee 6DOF kinematics were captured during level walking, 10% upslope walking, and landing task using a 3D motion capture system. The International Physical Activity Questionnaire (IPAQ), Visual Analogue Scale (VAS) for pain, and Kujala score were assessed at baseline and 18-month follow-up. Statistical parametric mapping (SPM1D) was used for kinematic analysis.
Results:
During level walking, the QA group showed greater internal rotation at 69-74% gait cycle (GC) (p = 0.042) and altered flexion/extension at 75-90% GC (p = 0.012). During upslope walking, the QA group exhibited different flexion/extension at 74-87% GC (p = 0.018). No kinematic differences were found in any 6DOF parameter during landing task. At 18 months, there were no significant intergroup differences in IPAQ, VAS, or Kujala scores (all p > 0.05).
Conclusion:
Q-angle asymmetry induces task- and phase-specific alterations in knee angular kinematics during walking tasks but does not affect translational kinematics or short-term functional outcomes in healthy young adults. Its biomechanical effect is limited and context-dependent, suggesting caution in using it as a standalone risk marker for knee injury.

