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Published on: September 16, 2019
Biopharmaceuticals for Cancer Treatment: An Update
Anupom Deb Nath1, Yousuf Alam2, Afsana Mustak Mim2
1Faculty of Biotechnology and Genetic Engineering, Sylhet Agricultural University, Sylhet, Bangladesh.
Abstract:
Cancer is one of the most debilitating diseases, causing profound physical and psychological impacts on patients. The global number of cancer patients has been steadily rising over the last few decades. The development of effective cancer therapies remains the primary focus in life science research, requiring a precise understanding of specific pathways and the regulation of tumor markers. The approved cancer therapies demonstrate effectiveness by acting on specific regulatory enzymes, components required for cell division, hormones, and cell-specific receptors, etc. While small-molecule drugs continue to dominate the market of cancer treatments, there has been a significant increase in the approval of biopharmaceutical drugs in recent years. These approved biopharmaceuticals are expanding the treatment options and extending the lives of millions of cancer patients. In this review, we explored the potential targets for developing anticancer drugs and discussed the application of approved anticancer biopharmaceutical drugs with current challenges and future perspectives.
Insights
This review explores potential anticancer drug targets and discusses approved biopharmaceutical cancer therapies, highlighting their expanding role in treatment and patient survival. It examines current challenges and future directions in cancer drug development.
Area of Science:
- Oncology
- Pharmacology
- Biotechnology
Background:
- Cancer presents a growing global health challenge with significant physical and psychological impacts.
- Effective cancer therapies are crucial, necessitating a deep understanding of tumor markers and regulatory pathways.
- Current treatments, including small-molecule drugs, are evolving with a rise in biopharmaceutical approvals.
Purpose of the Study:
- To review potential molecular targets for novel anticancer drug development.
- To discuss the clinical application and impact of approved anticancer biopharmaceutical drugs.
- To identify current challenges and future perspectives in the field of cancer biotherapeutics.
Main Methods:
- Literature review of existing cancer therapies and drug targets.
- Analysis of approved biopharmaceutical drugs for cancer treatment.
- Exploration of emerging trends and challenges in anticancer drug discovery.
Main Results:
- Identified key regulatory pathways and molecular targets relevant for anticancer drug development.
- Highlighted the increasing efficacy and patient life extension provided by approved biopharmaceutical agents.
- Summarized the diverse mechanisms of action for current cancer therapies, including small-molecule drugs and biopharmaceuticals.
Conclusions:
- Biopharmaceutical drugs represent a significant advancement in cancer treatment, expanding therapeutic options.
- Further research into specific pathways and targets is essential for developing more effective anticancer drugs.
- Addressing current challenges and embracing future perspectives will drive innovation in oncology drug development.
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