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Updated: Jul 13, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Intensive Swallowing Rehabilitation for Head and Neck Cancer Survivors With Chronic Dysphagia: Outcomes From a
J I Oldenbeuving1, L van der Molen2, J T Groothuis1
1Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Department of Rehabilitation, Nijmegen, the Netherlands.
Background:
Chronic dysphagia persists in some head and neck cancer (HNC) survivors despite preventive exercises, negatively impacting quality of life. Evidence for effective rehabilitation strategies remains limited.
Methods:
This prospective cohort study included 34 HNC survivors (≥ 1 year post-treatment) who completed a 3-week intensive swallowing rehabilitation (ISR) program (15 sessions, 60 min/day). Outcomes were measured at baseline (T0), post-treatment (T1), and 6-month follow-up (T2) using patient-rated (VAS, MDADI, PSS-HN), clinician-rated (food level, AUS-TOM), and objective swallowing outcomes (MSS, MSV, TOMASS).
Results:
ISR was feasible and safe (92% completion, no adverse events). Patient-rated and most clinician-rated outcomes improved significantly post-ISR and remained stable at 6 months (VAS: p < 0.001; PSS-HN: p < 0.001; food level: p = 0.002). MDADI and AUS-TOM for solids further improved at follow-up. Objective swallowing tests showed no clinically relevant change.
Conclusion:
ISR effectively improves normalcy of diet and quality of life in HNC survivors with chronic dysphagia, with benefits sustained at 6 months.
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