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Updated: Apr 11, 2026

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
Published on: July 12, 2021
[Febrile seizures in infants and children : know how to respond]
Roxane Zweifel1, Cosette Pharisa2, Youcef Guechi3
1Service de pédiatrie, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Insights
Febrile seizures are common in young children and usually resolve on their own. While recurrences happen in about 30%, the risk of long-term issues like epilepsy is very low.
Area of Science:
- Pediatrics
- Neurology
- Child Health
Background:
- Febrile seizures are the most common neurological disorder in children aged 6 months to 5 years.
- They occur in 2-4% of this age group.
- Diagnosis is primarily clinical, with tests used to exclude other conditions.
Purpose of the Study:
- To summarize the key aspects of febrile seizures.
- To differentiate between simple and complex febrile seizures.
- To outline diagnostic and treatment approaches.
Main Methods:
- Clinical diagnosis is central.
- Further investigations aim to rule out differential diagnoses.
- Treatment involves observation for simple cases and medication for prolonged seizures.
Main Results:
- Most febrile seizures are self-limiting, resolving within minutes.
- Emergency treatment with benzodiazepines or antiepileptic drugs may be required.
- Recurrence rates are approximately 30%.
Conclusions:
- The prognosis for febrile seizures is generally favorable.
- The risk of neurological sequelae is minimal.
- The risk of developing epilepsy later in life is very low.
Abstract:
Febrile seizures are the most common neurological disorder in infants and children. They affect children aged 6 months to 5 years with a frequency of 2 to 4 %. The diagnosis is clinical, and additional tests are mainly used to rule out other differential diagnoses. A distinction is made between simple febrile seizures and complex febrile seizures. Most febrile seizures stop spontaneously within a few minutes. If not, emergency treatment with benzodiazepines or even antiepileptic drugs is necessary. The prognosis is usually favourable. Recurrences are estimated at around 30 %. The risk of neurological sequelae is almost zero, while the risk of developing epilepsy later on is minimal.
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