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Updated: Apr 11, 2026

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Mechanism by which SAHA regulates HLA-E expression via the endoplasmic reticulum stress-related PERK/ATF4/CHOP

Zhuoran Li1, Xi Zhen2, Chenggong Zeng1

  • 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.

Frontiers in Immunology
|April 10, 2026
PubMed
Abstract

Keywords:
endoplasmic reticulum stress (ERS)human leukocyte antigen E (HLA-E)immune evasionneuroblastomasuberoylanilide hydroxamic acid (SAHA)

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