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Nomogram of Common Bile Duct Diameter in Children from a Tertiary Care Center in Central India: A Cross-sectional
Suresh Kumar Thanneeru1, Rajesh Malik2, Ankur Patel2
1Department of Paediatric Surgery, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Insights
Normal common bile duct diameter in children increases with age and liver span. This study establishes crucial reference values for pediatric common bile duct measurements in Central India, aiding in diagnosing conditions.
Area of Science:
- Pediatric Gastroenterology
- Medical Imaging
- Diagnostic Ultrasonography
Background:
- Accurate common bile duct (CBD) diameter measurements are vital for differentiating pediatric hepatobiliary conditions.
- Existing adult size criteria are inapplicable to children, and regional variations exist.
- There is a significant gap in pediatric CBD diameter literature, particularly from India.
Purpose of the Study:
- To establish reference standards for common bile duct (CBD) diameter in children from Central India.
- To investigate the correlation between CBD diameter, age, and liver span in pediatric populations.
- To provide data that aids in distinguishing pathological CBD dilation in children.
Main Methods:
- A cross-sectional observational study was conducted at a tertiary care center in Central India.
- Ultrasonography was used to measure the common bile duct (CBD) diameter in 131 children (1 month to 15 years) without hepatobiliary pathology.
- Sample size was determined using a formula to estimate the population mean.
Main Results:
- The mean CBD diameter showed a significant positive correlation with age (P < 0.001) and liver span (P < 0.001).
- CBD diameters varied significantly across age groups: under 1 year (1.01 ± 0.36 mm), 1-10 years (2.36 ± 0.94 mm), and over 10 years (2.77 ± 0.87 mm).
- No significant difference in CBD diameter was found between the 1-10 years and over 10 years age groups (P = 0.07).
Conclusions:
- Pediatric common bile duct (CBD) diameter positively correlates with both age and liver span.
- This study provides essential reference data for CBD diameter in children, specifically for Central India.
- The findings can assist clinicians in identifying and diagnosing pathologically dilated CBD in pediatric patients.
Background:
Normal common bile duct (CBD) diameter measurements are essential to distinguish from pathological conditions. The size criteria used for adults do not apply to children. There are differences among studies reported from various geographic regions. There is a lack of literature, particularly from India.
Methods:
A cross-sectional observational study was conducted at a tertiary care center in Central India. A sample size of 96 was calculated using a sample size formula to estimate the population mean. Children aged from newborns to 15 years old with no hepatobiliary pathology who required ultrasonography were included. The GE Logiq S8 ultrasound machine (GE Healthcare, Wauwatosa, WI, USA) was used to measure CBD diameter.
Results:
A total of 131 children were included, with a mean age of 6.05 ± 3.75 years (range: 1 month-14 years). The children were divided into three age groups: under 1 year (n = 13; CBD diameter: 1.01 ± 0.36), 1-10 years (n = 89; CBD diameter: 2.36 ± 0.94), and over 10 years (n = 19; CBD diameter: 2.77 ± 0.87). There is a significant difference in CBD diameters among the age groups (P < 0.001), with no significant difference between the 1-10 years and over 10 years groups (P = 0.07). In addition, there is a correlation between liver span and CBD diameter (P < 0.001).
Conclusion:
The mean CBD diameter in children showed a positive correlation with age and liver span. This data can serve as a reference standard for CBD diameter in children, especially in Central India. It may aid in distinguishing pathologically dilated CBD.

