Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Food Intake01:30

Regulation of Food Intake

3.2K
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
3.2K
Neural Regulation01:37

Neural Regulation

45.1K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
45.1K
Hormonal Regulation01:40

Hormonal Regulation

50.9K
Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
50.9K
Self-Regulation01:25

Self-Regulation

328
Self-regulation, also known as self-control, encompasses a range of cognitive and behavioral processes that allow individuals to adjust their internal states and outward actions to align with socially acceptable norms and long-term goals. It plays a fundamental role in adaptive functioning, from resisting impulsive behaviors to persisting through challenging tasks. While its benefits are widely recognized, self-regulation is not limitless. Muraven and Baumeister's theory posits that...
328
Binge Eating Disorders01:23

Binge Eating Disorders

786
Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
786
Regulation of the Digestive System01:25

Regulation of the Digestive System

4.0K
Digestive activity regulation hinges on three primary components. Activation is prompted by a multitude of mechanical and chemical indicators, primarily detected by receptors within the stomach and intestines' walls. These receptors predominantly respond to factors such as mechanical stretching of the organ walls, changes in pH and osmolarity, and the presence of digesting materials and their by-products.
The effectors in this regulation system are glands and smooth muscles. Activation of...
4.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Learning Shapes the Energy Cost of Neural Tasks.

bioRxiv : the preprint server for biology·2026
Same author

The Cluster Completeness Correction Calculator (c-4): a neural-network framework and pilot application to the LEGUS survey of NGC 628.

Monthly notices of the Royal Astronomical Society·2026
Same author

Functional Ultrasound Localization Microscopy on Freely Moving Rats.

Research square·2026
Same author

Adaptive Cavity-Enabled Crystalline Chirality in Nanocarbon Cages.

Angewandte Chemie (International ed. in English)·2026
Same author

Functional remodeling of the parasubthalamic nucleus drives alcohol drinking escalation in dependence.

bioRxiv : the preprint server for biology·2026
Same author

Radiomic signatures associated with longitudinal TNM downstaging for prognostic stratification in breast cancer.

Insights into imaging·2026

Related Experiment Video

Updated: Apr 11, 2026

Control of Eating Behavior Using a Novel Feedback System
04:48

Control of Eating Behavior Using a Novel Feedback System

Published on: May 8, 2018

11.8K

Top-down regulation of ingestive behavior fragmentation.

Tianbo Qi1,2, Colton Krull1,2, Verina H Leung1,2

  • 1Department of Neuroscience, Dorris Neuroscience Center, Scripps Research; San Diego, CA, USA.

Biorxiv : the Preprint Server for Biology
|April 10, 2026
PubMed
Summary

Animals pause feeding due to a neural circuit regulating bout duration. The dorsal subiculum (dSub) to mammillary body (MB) pathway controls feeding fragmentation, independent of hunger.

More Related Videos

Author Spotlight: Accessible M&M-Based Mouse Model for Investigating Binge Eating Disorder - Insights into Eating Behaviors, Anxiety, and Neural Mechanisms
05:15

Author Spotlight: Accessible M&M-Based Mouse Model for Investigating Binge Eating Disorder - Insights into Eating Behaviors, Anxiety, and Neural Mechanisms

Published on: January 10, 2025

1.9K
Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats
08:07

Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats

Published on: August 24, 2016

9.7K

Related Experiment Videos

Last Updated: Apr 11, 2026

Control of Eating Behavior Using a Novel Feedback System
04:48

Control of Eating Behavior Using a Novel Feedback System

Published on: May 8, 2018

11.8K
Author Spotlight: Accessible M&M-Based Mouse Model for Investigating Binge Eating Disorder - Insights into Eating Behaviors, Anxiety, and Neural Mechanisms
05:15

Author Spotlight: Accessible M&M-Based Mouse Model for Investigating Binge Eating Disorder - Insights into Eating Behaviors, Anxiety, and Neural Mechanisms

Published on: January 10, 2025

1.9K
Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats
08:07

Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats

Published on: August 24, 2016

9.7K

Area of Science:

  • Neuroscience
  • Behavioral Biology
  • Computational Neuroscience

Background:

  • Animals exhibit fragmented feeding patterns, not continuous eating.
  • The neural basis for this feeding behavior is not well understood.
  • Understanding this fragmentation is key to understanding action selection.

Purpose of the Study:

  • To identify the neural mechanisms regulating feeding bout fragmentation.
  • To investigate the role of the dorsal subiculum (dSub) and mammillary body (MB) in feeding behavior.
  • To model the neural dynamics underlying feeding fragmentation.

Main Methods:

  • Bidirectional neural activity mapping.
  • Behavioral phenotyping.
  • Optogenetic and behavioral perturbations.
  • Bistable attractor modeling.

Main Results:

  • A dSub-MB neural projection was identified as a key regulator of feeding bout duration.
  • dSub-MB pathway activity tracks and gates feeding bout length, irrespective of homeostatic state.
  • A bistable attractor model accurately predicted neural and behavioral responses.

Conclusions:

  • The dSub-MB circuit provides a top-down mechanism for controlling feeding fragmentation.
  • This circuit implements action selection in naturalistic feeding scenarios.
  • Neural dynamics in this pathway are crucial for behavioral timing.