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Clinical Presentation and Surgical Management of Pediatric Coronary Artery Disease: A Single-Center Retrospective

Khanh Van T Le1,2, Le Duc Tin3,4

  • 1Department of Pediatric Cardiac Surgery, Cho Ray Hospital, Ho Chi Minh, VNM.

Cureus
|April 10, 2026
PubMed

Insights

Pediatric coronary artery disease, though rare, presents diversely. Surgical intervention at a specialized center showed favorable early outcomes for children with complex coronary artery conditions.

Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Disease Surgery
  • Acquired Heart Disease in Children

Background:

  • Pediatric coronary artery disease (CAD) is uncommon but can lead to severe outcomes.
  • Limited data exists on CAD management in resource-limited settings.
  • Understanding clinical presentation and surgical strategies is crucial.

Purpose of the Study:

  • To describe the clinical features and surgical management of pediatric coronary artery disease.
  • To evaluate early outcomes of surgical interventions for pediatric CAD.
  • To highlight the heterogeneity of pediatric CAD etiologies.

Main Methods:

  • Retrospective case series of pediatric patients undergoing surgical intervention for CAD (2018-2025).
  • Analysis of demographic data, coronary pathology, surgical procedures, and early outcomes.
  • Single-center study at a tertiary cardiac surgery center.

Main Results:

  • Eight pediatric patients (median age 10 years) were included.
  • Common presentations included heart failure, fatigue, and chest pain.
  • Etiologies varied, including Kawasaki disease, anomalous coronary artery origin (e.g., ALCAPA), and coronary fistulas.
  • Coronary artery bypass grafting was the most common procedure (46%).
  • No early operative mortality was observed.

Conclusions:

  • Pediatric coronary artery disease is a heterogeneous condition requiring tailored surgical approaches.
  • Individualized surgical management in a tertiary center yielded positive early outcomes.
  • Further research is needed, especially from resource-limited settings.

Keywords:
coronary artery anomaliescoronary artery bypass graftingcoronary vessel surgerypediatric cardiac surgerypediatric coronary artery disease

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