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Interesting Cases of Intracerebral Haemorrhage Due to Underlying Cerebral Amyloid Angiopathy
Ayesha Khan1, Richard Marigold1
1Department of Stroke, University Hospital Southampton NHS Foundation Trust, Southampton, GBR.
Cerebral amyloid angiopathy (CAA) is a common small vessel disease occurring in older patients involving amyloid β deposition, which can lead to transient focal neurological symptoms similar to transient ischaemic attacks (TIAs), spontaneous intracerebral lobar haemorrhage and cognitive impairment. Diagnosis can guide interventions such as blood pressure lowering to reduce future risk of haemorrhage, as well as facilitate decision-making about patients who need to be on antithrombotic medication who are at high thrombotic risk. Using illustrative cases, we consider the variety of ways in which CAA may present, appropriate investigations and an approach to management.
Cerebral amyloid angiopathy (CAA) is a common small vessel disease occurring in older patients involving amyloid β deposition, which can lead to transient focal neurological symptoms similar to transient ischaemic attacks (TIAs), spontaneous intracerebral lobar haemorrhage and cognitive impairment. Diagnosis can guide interventions such as blood pressure lowering to reduce future risk of haemorrhage, as well as facilitate decision-making about patients who need to be on antithrombotic medication who are at high thrombotic risk. Using illustrative cases, we consider the variety of ways in which CAA may present, appropriate investigations and an approach to management.
