Featuring the application of biochemistry in dental practice through a self-directed assignment: A descriptive study
1Mike Petryk School of Dentistry, Faculty of Medicine & Dentistry, College of Health Sciences, University of Alberta, Canada.
Plos One
|April 10, 2026
Summary
A new biochemistry assignment improved dental hygiene students' understanding of protein structure and function. The interactive, case-based activity highlighted the relevance of biochemistry to dental practice, boosting student confidence and knowledge.
Area of Science:
- Biochemistry education for oral health professionals.
- Integration of foundational science into dental curricula.
Background:
- Cellular biochemistry knowledge is vital for modern oral health professionals.
- Dental students often struggle with foundational biochemistry, perceiving it as complex and irrelevant.
- A need exists to enhance student motivation and understanding of biochemistry's clinical applications.
Purpose of the Study:
- To develop and evaluate a focused, self-directed assignment for first-year Dental Hygiene (DH) students.
- To improve DH students' understanding of protein structure and function.
- To underscore the relevance of biochemistry to dental practice.
Main Methods:
- A quiz-style, self-directed assignment was created using Google Forms.
- The assignment was integrated as a supplementary activity in a foundational biochemistry course.
- Student perceptions and performance were analyzed using descriptive statistics.
Main Results:
- 86% of students completed the supplementary assignment, with an average score of 6.04/10.
- 60% of participants reported enhanced knowledge of protein structure-function relationships.
- 48% understood how protein sequence changes impact structure and function.
Conclusions:
- A well-designed, interactive assignment can stimulate student motivation in biochemistry.
- Highlighting biochemistry's application in dentistry enhances its perceived relevance.
- This approach shows potential for improving foundational science education in dental programs.


