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Biological Age as a Readout of Cerebral Small Vessel Disease: Inferring Brain Health From Systemic Clocks

Thomas Tourdias1,2,3, Michel Thiebaut De Schotten3,4

  • 1Neuroimagerie diagnostique et thérapeutique, CHU de Bordeaux, France.

Neurology
|April 10, 2026
PubMed
Abstract

No abstract available in PubMed .

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Biological Clocks and Seasonal Responses02:45

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The circadian—or biological—clock is an intrinsic, timekeeping, molecular mechanism that allows plants to coordinate physiological activities over 24-hour cycles called circadian rhythms. Photoperiodism is a collective term for the biological responses of plants to variations in the relative lengths of dark and light periods. The period of light-exposure is called the photoperiod.
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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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