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Airborne precautions:
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Ventilator-Associated Events: Surveillance and Prevention.

Marie-Céline Zanella1, Chanu Rhee2, Michael Klompas2

  • 1Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA; Infection Control Program and WHO Collaborating Centre, Faculty of Medicine, University of Geneva Hospitals, Geneva, Switzerland.

Infectious Disease Clinics of North America
|April 10, 2026
PubMed
Summary
This summary is machine-generated.

Ventilator-associated events (VAEs) are complications of mechanical ventilation linked to worse patient outcomes. Implementing VAE surveillance and specific care bundles can reduce VAE rates and improve patient safety.

Keywords:
Infection controlMechanical ventilationQuality improvementVentilator-associated eventsVentilator-associated pneumonia

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Area of Science:

  • Critical Care Medicine
  • Pulmonary Medicine
  • Infectious Disease Surveillance

Background:

  • Mechanical ventilation is essential but carries risks of complications.
  • Ventilator-associated events (VAEs) represent a spectrum of adverse outcomes during mechanical ventilation.
  • Objective surveillance is needed to identify and mitigate these complications.

Purpose of the Study:

  • To introduce the Ventilator-Associated Event (VAE) framework for surveillance.
  • To highlight the clinical significance and impact of VAEs.
  • To outline strategies for reducing VAE rates.

Main Methods:

  • Utilizing an objective and reproducible surveillance framework for VAEs.
  • Analyzing the association of VAEs with prolonged ventilation, ICU stay, and mortality.
  • Reviewing interventions aimed at VAE reduction.

Main Results:

  • VAEs are linked to increased mechanical ventilation duration, extended ICU stays, and higher mortality.
  • VAE rates are reducible through targeted interventions.
  • VAE surveillance serves as a valuable quality indicator.

Conclusions:

  • The VAE framework offers objective surveillance for mechanical ventilation complications.
  • Reducing VAEs can improve patient outcomes and enhance the safety of mechanical ventilation.
  • VAE surveillance aids in risk identification, benchmarking, and quality improvement initiatives.